January
Monday
Class 11-11:50am/Lab 
1-4pm
Tuesday
Wednesday
Class
11-11:50am
Thursday
Friday
Class
11-11:50am
 
14
15
16
17
topics

Intro to Class

Chem Review

pH & Buffers

Henderson-Hasselbalch

Intro to Case 1

 
20
21
22
23
24
topics
 
 
 

 

Amino Acids (group/station work)
 

 

 
 

 
 
 

 

Protein Functions

Aspirin Case Solutions Due 

QUIZ 1 (on-line)

 

Introduce protein structure

Computer modeling work stations

 
27
28
29
30
31
topics
 
 

 

Class: Quiz 2 (online)

Domains

Computer modeling work stations
 
Lab: WWW lab


 
 
 
 

 

Analysis of protein structure

Calculation of pI


 
 

 

Primary structure analysis

Computer modeling work with malate dehydrogenase

 

February
Monday
Tuesday
Wednesday
Thursday
Friday
 
3
4
5
6
7
topics
 
 
 
 

 

Computer modeling work stations:hemoglobin and myoglobin

Bohr efffect, bpg binding site

Quiz 3 (online)
 
Lab: Making Buffers 

 

Group presentations for Case 2

Prion Case Solutions Due


 

Computer modeling of Hemoglobin and myoglobin

Homology

cooperativity and allostery

 
10
11
12
13
14
topics
 
 
 
 
 

 

O2 binding

Hill Plots

 
Lab:   Protein Isolation

 

 

Case 3 Hemoglobin presentations and solutions due

Intro to enzyme kinetics

 

Review

 
17
18
19
20
21
topics
 
 
 
 
 

 

Snow Day


EXAM #1 

EXAM #1

Kinetics

EXAM #1
Mid-Semester Break
 
24
25
26
27
28
topics
 
 
 
 
 

 

Class: Kinetics
 
Lab:  proteins isolation, con't.
 
Kinetics
 
Mechansims
 
Mon
Tues
Wed
Thurs
Fri
March
3
4
5
6
7
topics
 
 
 
 

 

Class: Mechanisms/Regulation

Quiz 4 (online)
 
Lab:   Protein Isolation Continued

 
Cell signalling
 
Cell cycle
 
10
11
12
13
14
topics
 
 
 
 

 

Class: apoptosis

mutations, cancer risks

Quiz 5 (online)
 
Lab: beta-galactosidase kinetics

 
Case 4 phospatase presentations and solutions due
Exam 2
 
17
18
19
20
21
topics
 
 
 

 

Spring Break
Spring Break
Spring Break
Spring Break
Spring Break
 
24
25
26
27
28
topics
 
 
 
 

 

Class: Lipids
 
Lab: beta-galactosidase kinetics
Transport- diffusion, passive
Transport - active
April
31
1
2
3
4
topics
 
 
 
 

 

Class: Toxicology Case introduction
Lab: beta-galactosidase kinetics
 
Calculations
 
7
8
9
10
11
topics
 
 
 
 

 

Calculations continued

 

Lab: PCR/mutation

Case 5 Multidrug Transporter Case presentations and solutions due

 

Toxicology
 
14
15
16
17
18
topics
 
 
 
 

 

 

Class: Toxicology

General, risk assessment

Lab: PCR/mutation

 

 

Toxicology:

metals, chromium

 

Organic Toxicology- benzene

 

 
21
22
23
24
25
topics
 
 
 
 

 

 

Class: Organic Toxicology- benzene

Lab: PCR/mutation

 

Toxicology review

 

Exam 3
May
28
29
30
1
2
topics
 
 
 
 

 

 

Class:Group Presentation

Lab: Review for Final

 

 

 

Group Presentation

 

 

 

Group Presentation

Last Day of Class!

5
6
7
8
9
topics
 
 
 
 

 

   

 

 

Final Exam 2:00 pm