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Harold Varmus, Science, Government, and the Public Interest, the William D. Carey lecture delivered at the AAAS Forum on Science and Technology Policy (Washington, D.C., April 21-22). Excerpt: 'This dream of freely accessible public knowledge has been around for a long time, long before the digital age. In 1836, the head of the British Library said: "I want a poor student to have the same means of indulging his learned curiosity, of following his rational pursuits, of consulting the same authorities, of fathoming the most intricate inquiry as the richest man in the kingdom...." We now have the technical tools to make this vision a reality. The advantages to scientists, to students, and to the growing number of interested citizens everywhere in the world are obvious. What stands in the way? First, concerns about how we will pay the costs of open access publishing. But these costs will inevitably be less overall than the escalating and increasingly unaffordable costs of the traditional, subscription-based, restrictive model of publishing that we currently use. And government is already covering most of those costs in the US, through grants that pay for laboratory subscriptions, for page and color charges, and, through indirect payments, for libraries. Second, concerns about the fate of scientific societies that support other worthwhile activities with revenues from their journals. There is no doubt that some societies, those dependent on such revenues, will have to adjust their business plans and obtain more revenue from membership fees, meetings, and other services. The first objective of any scientific society, just like any union or guild, should be to optimize the working conditions for its scientists; surely making the scientific record freely accessible and more usable should be the paramount consideration. Third, concerns about the survival of revered and expensive-to-produce journals like Science and Nature. But the open access movement is addressed to primary research reports, not to the costly, entertaining, and important "front matter" of these journals---the news, editorials, obituaries, gossip, book reviews, and mini-reviews.....The government also has a role to play here. Publication should be viewed as part of the cost of doing research (in most fields it is also a very small part of the cost, less than 1%); the government should expect to pay publication costs, even when they are shifted from reader to author, just as they do now; and rapid open dissemination will augment the value of the research by promoting its use as a public good. A firm statement of those principles, including an expectation that science supported by public money will be publicly available, will help cement the resolve of scientists, who know that open access publication should and will happen, to make it happen soon.'
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