Open Access News

News from the open access movement


Thursday, May 05, 2005

More on the ACS complaint against PubChem

Jocelyn Kaiser, Chemists want NIH to curtail database, Science Magazine, May 6, 2005 (accessible only to subscribers). Excerpt: 'The American Chemical Society (ACS) wants the U.S. government to shut down a free database that it says duplicates the society's fee-based Chemical Abstracts Service (CAS). Government officials defend the site, called PubChem, saying the two serve different purposes and will complement, rather than compete with, each other. But ACS officials are hoping to convince Congress to stop PubChem unless the government scales it back....So far, PubChem includes information on 650,000 compounds, such as structures and biological assays, as well as links to PubMed, NIH's free biomedical abstracts database. It will grow to include data from the Molecular Libraries centers, which aim to screen thousands of molecules for biological activity. NIH expects basic researchers to use PubChem to identify chemicals they can use to explore how genes and cells work....But ACS claims PubChem goes far beyond a chemical probes database. It is, ACS says, a smaller version of CAS, which employs more than 1200 people in Columbus, Ohio, and makes a significant contribution to the society's $317 million in annual revenue from publications. Institutional subscribers receive data on 25 million chemicals, including summaries written by CAS experts and links to chemistry journal abstracts....Claiming that PubChem could wipe out CAS, Jacobs argues that NIH should abide by its stated mission of storing only data from the Molecular Libraries Initiative and other NIH-funded research....NIH officials counter that PubChem indexes a set of biomedical journals that overlaps only slightly with those CAS indexes and, unlike CAS, does not provide curated information on patents or reactions. "They have a vast amount of information that PubChem would never dream of including," says Francis Collins, director of the National Human Genome Research Institute. PubChem's focus on biological information such as protein structures and toxicology is complementary, he says. NIH has offered to link entries in PubChem to CAS, but ACS says that wouldn't help.' (Thanks to George Porter.)