Open Access News

News from the open access movement


Friday, January 16, 2009

Fixing the system of OA for clinical drug trial data

M. Antonelli and G. Mercurio, Reporting, access, and transparency: better infrastructure of clinical trials, Critical Care Medicine, January 2009 (1 Supplement).  I can't find this in the journal TOC, so I'm linking to the record at PubMed. 

Abstract:   Open access to information in medical science and adequate reporting of clinical trials may allow investigators and editors to recognize bias in study designs and avoid unnecessary duplication of efforts. Unfortunately, most of clinical trials are very expensive and are often supported by industries that may have financial reasons to hide or partially disclose results. However, investigators and editors have a greater interest in publishing results that can immediately change clinical practice rather than negative results, thus contributing to facilitate publication biases. Several years ago, legislation in several countries mandated the registration of clinical trials as an effective means of promoting information access and full transparency in medical research. However, comprehensive registers have not been adequately supported by law, particularly in Europe, where legislation has ironically contributed to fragmented research, and dampened its competitiveness and productivity. In this context, appropriate strategies help to protect the independence of academic research and ensure full transparency in medical science.